Article
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
Oncotarget - 6 Oct 2015
Ren Ling, Mendoza Arnulfo, Zhu Jack, Briggs Joseph W, Halsey Charles, Hong Ellen S, Burkett Sandra S, Morrow James, Lizardo Michael M, Osborne Tanasa, Li Samuel Q, Luu Hue H, Meltzer Paul, Khanna Chand
Abstract excerpt
Osteosarcoma (OS) is the most common bone tumor in pediatric patients. Metastasis is a major cause of mortality and morbidity. The rarity of this disease coupled with the challenges of drug development for metastatic cancers have slowed the delivery of improvements in long-term outcomes for these patients. In this study, we collected 18 OS cell lines, confirmed their expression of bone markers and complex...
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