Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition.

doi:10.1016/j.bbr.2015.08.028

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition.

Behavioural brain research - 1 Jan 2016

Salminen Lauren E, Schofield Peter R, Pierce Kerrie D, Zhao Yi, Luo Xi, Wang Youdan, Laidlaw David H, Cabeen Ryan P, Conturo Thomas E, Tate David F, Akbudak Erbil, Lane Elizabeth M, Heaps Jodi M, Bolzenius Jacob D, Baker Laurie M, Cagle Lee M, Paul Robert H

Abstract excerpt

The common angiotensinogen (AGT) M268T polymorphism (rs699; historically referred to as M235T) has been identified as a significant risk factor for cerebrovascular pathologies, yet it is unclear if healthy older adults carrying the threonine amino acid variant have a greater risk for white matter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensinogen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Attention

Share to Diffusion Tensor Imaging

Share to Language

Share to Neural Pathways

Share to Psychomotor Performance

Share to Threonine

Share to White Matter

Source

Open in PubMed Open full text

Identifiers

PMID: 26318936
DOI: 10.1016/j.bbr.2015.08.028
PMCID: PMC4692153

Genes

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26318936-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition.PMID 26318936Read ↗

Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype.Semantic proximity Read ↗

Impact of the AGTR1 A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults.Semantic proximity Read ↗

BDNF Val66Met Moderates the Effects of Hypertension on Executive Functioning in Older Adults Diagnosed With aMCI.Semantic proximity Read ↗

White matter integrity in the splenium of the corpus callosum is related to successful cognitive aging and partly mediates the protective effect of an ancestral polymorphism in ADRB2.Semantic proximity Read ↗

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.Semantic proximity Read ↗

Sex, racial, and <i>APOE</i> -ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer’s diseaseSemantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease.Semantic proximity Read ↗

Magnified effects of the COMT gene on white-matter microstructure in very old age.Semantic proximity Read ↗

Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.Semantic proximity Read ↗

Structural Brain Indicators of Cognitive Performance in Middle and Late Adulthood: The Human Connectome Project in Aging/Aging Adult Brain Connectome CohortSemantic proximity Read ↗

Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age.Semantic proximity Read ↗

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.