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Article

Copy number variations primed lncRNAs deregulation contribute to poor prognosis in colorectal cancer

22 Aug 2019

Abstract excerpt

Copy number variations (CNVs) are crucial genetic change elements in malignancies, and lncRNAs deregulation induced by genomic and epigenomic aberrations plays key driving role in tumorigenesis, including colorectal cancer (CRC). However, effects of CNVs associated with lncRNAs in CRC is largely unknown. Here, we perform integrative analysis considering messenger RNA expression levels, DNA methylation and DNA...

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PMID: 31442207
DOI: 10.18632/aging.102168

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