Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2015

Walker Andreas, Siemann Holger, Groten Svenja, Ross R Stefan, Scherbaum Norbert, Timm Jörg

Abstract excerpt

BACKGROUND: People who inject drugs (PWID) are the most important risk group for incident Hepatitis C virus (HCV) infection. In PWID in Europe HCV genotype 3a is highly prevalent. Unfortunately, many of the recently developed directly acting antiviral drugs against HCV (DAAs) are suboptimal for treatment of this genotype. Detection of resistance-associated variants (RAV) in genotype 3a may help to optimize...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral
Share to Drug Users

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germany

Share to Hepacivirus

Share to Hepatitis C

Share to Prevalence

Share to Public Health Surveillance

Share to Viral Nonstructural Proteins

Source

Identifiers

PMID: 26305818
DOI: 10.1016/j.jcv.2015.07.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany.PMID 26305818Read ↗

Resistance analysis and treatment outcomes in hepatitis C virus genotype 3-infected patients within the Italian network VIRONET-C.Semantic proximity Read ↗

Frequency distribution of HCV resistance-associated variants in infected patients treated with direct-acting antivirals.Semantic proximity Read ↗

HCV NS3 naturally occurring variants in HIV/HCV coinfected DAA-naïve patients: consideration for HCV genotyping resistance testing.Semantic proximity Read ↗

Prevalence of naturally occurring NS5A resistance-associated substitutions in patients infected with hepatitis C virus subtype 1a, 1b, and 3a, co-infected or not with HIV in BrazilSemantic proximity Read ↗

Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug usersSemantic proximity Read ↗

Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies.Semantic proximity Read ↗

Prevalence of polymorphisms with significant resistance to NS5A inhibitors in treatment-naive patients with hepatitis C virus genotypes 1a and 3a in Sweden.Semantic proximity Read ↗

Prevalence of Single and Multiple Natural NS3, NS5A and NS5B Resistance-Associated Substitutions in Hepatitis C Virus Genotypes 1-4 in Italy.Semantic proximity Read ↗

HCV genotypes, characterization of mutations conferring drug resistance to protease inhibitors, and risk factors among blood donors in São Paulo, Brazil.Semantic proximity Read ↗

Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis CSemantic proximity Read ↗

Prevalence of resistance-associated substitutions and phylogenetic analysis of hepatitis C virus infection in Russia.Semantic proximity Read ↗

Injecting drug use: A vector for the introduction of new hepatitis C virus genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.