Association of polymorphisms of complement factor I rs141853578 (G119R) with age-related macular degeneration in Iranian population.

doi:10.1007/s10792-018-0835-0

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Article

Association of polymorphisms of complement factor I rs141853578 (G119R) with age-related macular degeneration in Iranian population.

International ophthalmology - 1 Mar 2019

Bonyadi Mortaza, Norouzi Neda, Babaei Esmaeil, Jabbarpoor Bonyadi Mohammad Hossein, Javadzadeh Alireza, Yaseri Mehdi, Soheilian Masoud

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a complex disease, and recent studies have shown role of complement system genes in its development. Complement factor I regulates the complement pathways, and relationship between CFI polymorphisms and AMD is controversial. We evaluated the possible association of complement factor I rs141853578 (G119R) variation with advanced AMD in Iranian patients....

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PMID: 29392637
DOI: 10.1007/s10792-018-0835-0

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