Article
The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.
BMC medical genetics - 14 Jun 2010
Zhao Jianhua, Li Mingyao, Bradfield Jonathan P, Zhang Haitao, Mentch Frank D, Wang Kai, Sleiman Patrick M, Kim Cecilia E, Glessner Joseph T, Hou Cuiping, Keating Brendan J, Thomas Kelly A, Garris Maria L, Deliard Sandra, Frackelton Edward C, Otieno F George, Chiavacci Rosetta M, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A
Abstract excerpt
BACKGROUND: Human height is considered highly heritable and correlated with certain disorders, such as type 2 diabetes and cancer. Despite environmental influences, genetic factors are known to play an important role in stature determination. A number of genetic determinants of adult height have already been established through genome wide association studies. METHODS: To examine 51 single nucleotide...
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