Article
Toll-like receptor-3 gene polymorphism in patients with Japanese encephalitis.
Journal of neuroimmunology - 15 Sept 2015
Biyani Sumant, Garg Ravindra Kumar, Jain Amita, Malhotra Hardeep Singh, Kumar Rashmi, Prakash Shantanu, Verma Rajesh, Sharma Praveen Kumar
Abstract excerpt
INTRODUCTION: Japanese encephalitis (JE) is one of the most lethal mosquito-borne viral encephalitis seen in India. Toll-like receptors (TLRs) play a critical role in host defence mechanism against flaviviruses causing encephalitis. We assessed whether abnormalities in toll-like receptor (TLR3) increase the susceptibly for JE. METHOD: A total of 103 JE patients (all from an endemic area) and 103 healthy control...
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