Article
Rare Chromones from a Fungal Mutant of the Marine-Derived Penicillium purpurogenum G59.
Marine drugs - 18 Aug 2015
Xia Ming-Wen, Cui Cheng-Bin, Li Chang-Wei, Wu Chang-Jing, Peng Ji-Xing, Li De-Hai
Abstract excerpt
Three new and rare chromones, named epiremisporine B (2), epiremisporine B1 (3) and isoconiochaetone C (4), along with three known remisporine B (1), coniochaetone A (5) and methyl 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate (6) were isolated from a mutant from the diethyl sulfate (DES) mutagenesis of a marine-derived Penicillium purpurogenum G59. The structures of 2-4 including the absolute configurations...
Topics
- Antineoplastic Agents
- Aquatic Organisms
- Cell Line, Tumor
- Chromones
- Circular Dichroism
- Fungi
- Humans
- K562 Cells
- Magnetic Resonance Spectroscopy
- Mutation
- Penicillium
- Sulfuric Acid Esters
