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Article

Novel factor H mutation associated with familial membranoproliferative glomerulonephritis type I.

Pediatric nephrology (Berlin, Germany) - 1 Dec 2015

Alfandary Hadas, Davidovits Miriam

Abstract excerpt

BACKGROUND: Idiopathic membranoproliferative glomerulonephritis (MPGN) is a rare disease, accounting for 3-5% of all cases of primary nephritic syndrome. We report an uncommon case of familial MPGN type I associated with a new mutation in the complement factor H gene (CFH). METHODS: Clinical data were collected on three siblings with known factor H deficiency who presented with MPGN. All underwent immunological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Genetic Predisposition to Disease

Share to Glomerulonephritis, Membranoproliferative

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Source

Identifiers

PMID: 26289290
DOI: 10.1007/s00467-015-3166-7

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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