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Article

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene.

The Journal of investigative dermatology - 1 Dec 2015

Perez Carlos J, Mecklenburg Lars, Jaubert Jean, Martinez-Santamaria Lucia, Iritani Brian M, Espejo Alexsandra, Napoli Eleonora, Song Gyu, Del Río Marcela, DiGiovanni John, Giulivi Cecilia, Bedford Mark T, Dent Sharon Y R, Wood Richard D, Kusewitt Donna F, Guénet Jean-Louis, Conti Claudio J, Benavides Fernando

Abstract excerpt

Here we describe a spontaneous mutation in the Zdhhc13 (zinc finger, DHHC domain containing 13) gene (also called Hip14l), one of 24 genes encoding palmitoyl acyltransferase (PAT) enzymes in the mouse. This mutation (Zdhhc13luc) was identified as a nonsense base substitution, which results in a premature stop codon that generates a truncated form of the ZDHHC13 protein, representing a potential loss-of-function...

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Identifiers

PMID: 26288350
DOI: 10.1038/jid.2015.314
PMCID: PMC4898190

Genes

ZDHHC13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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