Article
The Spectrum of α-Thalassemia Mutations in Kermanshah Province, West Iran.
Hemoglobin - 1 Jan 2015
Alibakhshi Reza, Mehrabi Masomeh, Omidniakan Leila, Shafieenia Samaneh
Abstract excerpt
Thalassemia is a hereditary blood disorder that results from genetic defects causing deficient synthesis of hemoglobin (Hb) polypeptide chains. Although thalassemia mostly affects developing countries, there is limited knowledge of its accurate frequency and distribution in these regions. Knowing the prevalence of thalassemia and the frequency of responsible mutations is therefore an important step in the...
Topics
- DNA Mutational Analysis
- Erythrocyte Indices
- Female
- Genotype
- Heterozygote
- Humans
- Iran
- Male
- Mutation
- Phenotype
- alpha-Globins
- alpha-Thalassemia