Article
The spectrum of β-thalassemia mutations in Kermanshah Province in West Iran and its association with hematological parameters.
Hemoglobin - 1 Jan 2013
Mehrabi Masomeh, Alibakhshi Reza, Fathollahi Soheila, Farshchi Mohammad Reza
Abstract excerpt
β-Thalassemia (β-thal) is a hereditary autosomal disorder with decreased or absent β-globin chain synthesis. Two hundred and one unrelated β-thal carriers, attending the Kermanshah Medical Genetics Laboratory, Kermanshah, Iran, were investigated for β-globin gene mutations by amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) and direct sequencing. Eighteen different mutations were...
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