Article
The Spectrum of α-Thalassemia Mutations in Kurdistan Province, West Iran.
Hemoglobin - 1 May 2020
Alibakhshi Reza, Moradi Keivan, Aznab Mozaffar, Dastafkan Zahra, Tahmasebi Susan, Ahmadi Mahsa, Omidniakan Leila
Abstract excerpt
In order to identify the α-thalassemia (α-thal) mutation spectrum in Kurdistan Province, West Iran, a total of 217 individuals, including 154 α-thal carriers and 63 normal subjects were investigated in this study. Molecular analysis of α1- and α2-globin genes using multiplex gap-polymerase chain reaction (gap-PCR), amplification refractory mutation system (ARMS)-PCR or direct DNA sequencing, showed 11 different...
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