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Article

Chromosome Y genetic variants: impact in animal models and on human disease.

Physiological genomics - 1 Nov 2015

Prokop J W, Deschepper C F

Abstract excerpt

Chromosome Y (chrY) variation has been associated with many complex diseases ranging from cancer to cardiovascular disorders. Functional roles of chrY genes outside of testes are suggested by the fact that they are broadly expressed in many other tissues and correspond to regulators of basic cellular functions (such as transcription, translation, and protein stability). However, the unique genetic properties of...

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Identifiers

PMID: 26286457
DOI: 10.1152/physiolgenomics.00074.2015
PMCID: PMC4629007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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