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Article

Genomics and genetics of human and primate y chromosomes.

Annual review of genomics and human genetics - 1 Jan 2012

Hughes Jennifer F, Rozen Steve

Abstract excerpt

In mammals, the Y chromosome plays the pivotal role in male sex determination and is essential for normal sperm production. Yet only three Y chromosomes have been completely sequenced to date--those of human, chimpanzee, and rhesus macaque. While Y chromosomes are notoriously difficult to sequence owing to their highly repetitive genomic landscapes, these dedicated sequencing efforts have generated tremendous...

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PMID: 22483277
DOI: 10.1146/annurev-genom-090711-163855

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Source receipt: pubmed, retrieved 7 Sept 2026.

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