Article
Risk given by AGT polymorphisms in inducing susceptibility to essential hypertension among isolated populations from a remote region of China: A case-control study among the isolated populations.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2015
Li Qian, Sun Lijuan, Du Jing, Ran Pengzhan, Gao Tangxin, Yuan Yuncang, Xiao Chunjie
Abstract excerpt
INTRODUCTION: Hypertension is a serious risk factor affecting up to 30% of the world's population with a heritability of more than 30-50%. The aim of this study was to investigate the contribution of the polymorphisms localized in the angiotensinogen (AGT) gene, a main component of the renin-angiotensin-aldosterone system, in inducing the susceptibility to essential hypertension (EH) among isolated populations...
Topics
- Alleles
- Angiotensinogen
- Blood Pressure
- Case-Control Studies
- China
- Computational Biology
- Diastole
- Essential Hypertension
- Ethnicity
- Genetic Association Studies