Article
Abnormal retinal development in Cloche mutant zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2015
Dhakal Susov, Stevens Craig B, Sebbagh Meyrav, Weiss Omri, Frey Ruth A, Adamson Seth, Shelden Eric A, Inbal Adi, Stenkamp Deborah L
Abstract excerpt
BACKGROUND: Functions for the early embryonic vasculature in regulating development of central nervous system tissues, such as the retina, have been suggested by in vitro studies and by in vivo manipulations that caused additional ocular vessels to develop. Here, we use an avascular zebrafish embryo, cloche-/- (clo-/-), to begin to identify necessary developmental functions of the ocular vasculature in regulating...
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