Article
Novel method for genotyping clinical herpes simplex virus type 1 isolates.
Archives of virology - 1 Nov 2015
Glück Brigitte, Möbius Susanne, Pfaff Florian, Zell Roland, Sauerbrei Andreas
Abstract excerpt
Up to now, three distinct genotypes, A, B and C, of herpes simplex virus type 1 (HSV-1), based on polymorphisms in the US4 and US7 genes, have been reported. Here, we propose to include an additional polymorphism of the US2 gene. The refined genotyping method was validated using 423 clinical isolates from patients with different HSV-1 diseases. The proportions of three US2 genotypes were A, 46.6%; B, 23.2%; and...
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