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Article

Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations.

Journal of clinical epidemiology - 1 Sept 2015

Patel Chirag J, Burford Belinda, Ioannidis John P A

Abstract excerpt

OBJECTIVES: Model specification-what adjusting variables are analytically modeled-may influence results of observational associations. We present a standardized approach to quantify the variability of results obtained with choices of adjustments called the "vibration of effects" (VoE). STUDY DESIGN AND SETTING: We estimated the VoE for 417 clinical, environmental, and physiological variables in association with...

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Identifiers

PMID: 26279400
DOI: 10.1016/j.jclinepi.2015.05.029
PMCID: PMC4555355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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