Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

doi:10.1161/JAHA.115.001853

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Article

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Journal of the American Heart Association - 14 Aug 2015

Persson Jonas, Strawbridge Rona J, McLeod Olga, Gertow Karl, Silveira Angela, Baldassarre Damiano, Van Zuydam Natalie, Shah Sonia, Fava Cristiano, Gustafsson Stefan, Veglia Fabrizio, Sennblad Bengt, Larsson Malin, Sabater-Lleal Maria, Leander Karin, Gigante Bruna, Tabak Adam, Kivimaki Mika, Kauhanen Jussi, Rauramaa Rainer, Smit Andries J, Mannarino Elmo, Giral Philippe, Humphries Steve E, Tremoli Elena, de Faire Ulf, Lind Lars, Ingelsson Erik, Hedblad Bo, Melander Olle, Kumari Meena, Hingorani Aroon, Morris Andrew D, Palmer Colin N A, Lundman Pia, Öhrvik John, Söderberg Stefan, Hamsten Anders

Abstract excerpt

BACKGROUND: Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT. METHODS AND RESULTS: Baseline plasma adiponectin concentration was tested for association with...

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PMID: 26276317
DOI: 10.1161/JAHA.115.001853
PMCID: PMC4599454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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