Article
Adiponectin level as a consequence of genetic variation, but not leptin level or leptin: adiponectin ratio, is a risk factor for carotid intima-media thickness.
Stroke - 1 Jun 2011
Bevan Steve, Meidtner Karina, Lorenz Matthias, Sitzer Matthias, Grant Peter J, Markus Hugh S
Abstract excerpt
BACKGROUND AND PURPOSE: The adipocytokines adiponectin and leptin have been suggested as risk factors for cardiovascular disease, including stroke, acting through atherosclerosis. However, studies have provided conflicting results in underpowered cohorts with some suggesting that the leptin:adiponectin ratio is a better predictor of risk. We examined these associations with carotid intima-media thickness (IMT), a...
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