Article
Mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus: therapeutic and evolutionary implications.
Molecular microbiology - 1 Dec 2015
Neubauer Michael, Zhu Zhaojun, Penka Mirjam, Helmschrott Christoph, Wagener Nikola, Wagener Johannes
Abstract excerpt
Mitochondria within eukaryotic cells continuously fuse and divide. This phenomenon is called mitochondrial dynamics and crucial for mitochondrial function and integrity. We performed a comprehensive analysis of mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus. Phenotypic characterization of respective mutants revealed the general essentiality of mitochondrial fusion for mitochondrial genome...
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