Article

Transient mitochondria dysfunction confers fungal cross-resistance between macrophages and fluconazole

2021-01-17

Abstract excerpt

<h4>ABSTRACT</h4> Loss or inactivation of antivirulence genes is an adaptive strategy in pathogen evolution. Candida glabrata is an important opportunistic pathogen related to baker’s yeast, with the ability to both, quickly increase its intrinsic high level of azole resistance and persist within phagocytes. During C. glabrata ’s evolution as a pathogen, the mitochondrial DNA polymerase, CgMip1, has been under...

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Literature Corpus work: 49350408-379b-517b-b534-0d80e49b841f
DOI: 10.1101/2021.01.14.426672

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