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Article

Evidence that the endosomal sorting complex required for transport-II (ESCRT-II) is required for efficient human immunodeficiency virus-1 (HIV-1) production.

Retrovirology - 14 Aug 2015

Meng Bo, Ip Natasha C Y, Prestwood Liam J, Abbink Truus E M, Lever Andrew M L

Abstract excerpt

BACKGROUND: Egress of a number of different virus species from infected cells depends on proteins of the endosomal sorting complexes required for transport (ESCRT) pathway. HIV has also hijacked this system to bud viruses outward from the cell surface. How ESCRT-I activates ESCRT-III in this process remains unclear with conflicting published evidence for the requirement of ESCRT-II which fulfils this role in...

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Identifiers

PMID: 26268989
DOI: 10.1186/s12977-015-0197-x
PMCID: PMC4535389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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