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Vps4 and the ESCRT-III complex are required for the release of infectious hepatitis C virus particles

14 Oct 2009

Abstract excerpt

The mechanisms by which infectious hepatitis C virus (HCV) particles are assembled and released from infected cells remain poorly characterized. In this regard, many other enveloped viruses, notably human immunodeficiency virus type 1, have been shown to utilize the host vacuolar protein sorting machinery (also known as the endosomal sorting complex required for transport; ESCRT) to traffic through the cell and...

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PMID: 19828764
DOI: 10.1099/vir.0.017285-0

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