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Article

[Effect of CCM3 gene defect on lead-induced cell genotoxicity in mouse embryonic fibroblasts].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Mar 2015

Su Xiaolin, Xing Xiumei, Lai Guanchao, Sun Yi, Zhao Zhiqiang, Chen Jingli, Shen Biling, Liu Xinxia, He Yun

Abstract excerpt

OBJECTIVE: To investigate the effect of CCM3 gene defection on lead induced cell genotoxicity in mouse embryonic fibroblasts. METHODS: C57 female mice were mated with CCM3 gene heterozygous male mice. E13.5 embryos were taken to isolate primary mouse embryonic fibroblasts. After genotyping, wild type and heterozygous cells were treated with different doses of lead acetate. Cell viability, genotoxicity and protein...

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PMID: 26268874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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