[Study of the mutagenic activity of cadmium by the method of dominant lethal mutation].

Article

[Study of the mutagenic activity of cadmium by the method of dominant lethal mutation].

Voprosy pitaniia - 1 Jan 1995

Volkova N A, Karpliuk I A, Emel'ianova E V

Abstract excerpt

Calculation of dominant lethal mutations was executed in intact female mouse, mated with male on 1 and 6 week after single intragastric ingestion maximum tolerated dose CdCl2 (2 mg of Cd per kg of body mass). The increase of total, pre- and postimplantation lethality was found within first 4 week...

Topics

Animals
Cadmium
DNA Repair
Embryo, Mammalian
Female
Genes, Dominant
Genes, Lethal
Male
Mice
Models, Biological
Mutagenicity Tests
Mutation
Pregnancy
Spermatogenesis

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