Tumor Heterogeneity: Focus on the Leaves, the Trees, or the Forest?

Abstract excerpt

Molecular studies of intra-tumor heterogeneity (ITH) are revealing a large amount of DNA-based variation in many individual tumors. In a recent publication by Yates and colleagues, the ITH of breast tumors was examined and shown to have important implications for the development of resistant disease, metastasis, and clinical sequencing efforts.

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