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Article

Dissecting ancestry genomic background in substance dependence genome-wide association studies.

Pharmacogenomics - 1 Jan 2015

Polimanti Renato, Yang Can, Zhao Hongyu, Gelernter Joel

Abstract excerpt

AIMS: To understand the role of ancestral genomic background in substance dependence (SD) genome-wide association studies (GWAS), we analyzed population diversity at genetic loci associated with SD traits and evaluated its effect on GWAS outcomes. MATERIALS & METHODS: We investigated 24 genes with variants associated with SD by GWAS; and 82 loci with putative subordinate roles with respect to SD-associated genes....

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Source

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Identifiers

PMID: 26267224
DOI: 10.2217/pgs.15.91
PMCID: PMC4632979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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