Article
Effect of lentiviral vector overexpression α-calcitonin gene-related peptide on titanium implant osseointegration in α-CGRP-deficient mice.
Bone - 1 Jan 2017
Xiang Lin, Ma Li, Wei Na, Wang Tianlu, Yao Qianqian, Yang Bo, Xiong Yi, Wu Yingying, Gong Ping
Abstract excerpt
α-Calcitonin gene-related peptide (α-CGRP) plays a significant pathophysiological role in bone development, metabolism and remodeling around dental implants. However, the half-life of α-CGRP in plasma is only 10min, which affects its long-time application and an alternative approach should be developed to deliver α-CGRP over long periods of time. The aim of this study is to investigate whether a lentiviral α-CGRP...
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