Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer.

International journal of cancer - 1 Feb 2016

Permuth-Wey Jennifer, Fulp William J, Reid Brett M, Chen Zhihua, Georgeades Christina, Cheng Jin Q, Magliocco Anthony, Chen Dung-Tsa, Lancaster Johnathan M

Abstract excerpt

Cancer stem cells (CSC) contribute to epithelial ovarian cancer (EOC) progression and therapeutic response. We hypothesized that germline single nucleotide polymorphisms (SNPs) in CSC-related genes may predict an initial therapeutic response for women newly diagnosed with EOC. A nested case-control design was used to study 361 women with advanced-stage serous EOC treated with surgery followed by first-line...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ovarian Epithelial
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cystadenocarcinoma, Serous

Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

Share to Platinum

Share to Receptor, Notch1

Share to STAT3 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 26264211
DOI: 10.1002/ijc.29799
PMCID: PMC4819434

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer.PMID 26264211Read ↗

Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.Semantic proximity Read ↗

Genetic variations in stem cell-related genes and colorectal cancer prognosis.Semantic proximity Read ↗

Common variants at 19p13 are associated with susceptibility to ovarian cancer.Semantic proximity Read ↗

Transcriptome-based Stemness Indices Analysis Reveals Platinum-based Chemotheraputic Response Indicators in Advanced-stage Serous Ovarian CancerSemantic proximity Read ↗

An Integrative Transcriptomic Analysis of a Stemness-Associated Gene Set on Ovarian Cancer RecurrenceSemantic proximity Read ↗

New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic toolsSemantic proximity Read ↗

Discovery analysis of TCGA data reveals association between germline genotype and survival in ovarian cancer patients.Semantic proximity Read ↗

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer.Semantic proximity Read ↗

Association of cancer stem cell markers genetic variants with gallbladder cancer susceptibility, prognosis, and survival.Semantic proximity Read ↗

CHST9 rs1436904 genetic variant contributes to prognosis of triple-negative breast cancer.Semantic proximity Read ↗

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome.Semantic proximity Read ↗

The discovery and evaluation of treatment stratification biomarkers in epithelial ovarian cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.