Article

Transcriptome-based Stemness Indices Analysis Reveals Platinum-based Chemotheraputic Response Indicators in Advanced-stage Serous Ovarian Cancer

2020-10-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Serous ovarian cancer (SOC) is a main histological subtype of ovarian cancer (OC). Cancer stem cells (CSCs), with self-renewal and differentiation potential, are considered to be the cause of chemoresistance in SOC. However, the underlying modulation mechanisms of chemoresistance led by cancer stemness are still undefined. <bold>Results: </bold>We found that mRN...

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Literature Corpus work: 59f6b940-ac4e-53ff-b772-553d88cf6f55
DOI: 10.21203/rs.3.rs-84140/v1

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