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Article

Novel monogenic diseases causing human autoimmunity.

Current opinion in immunology - 1 Dec 2015

Melki Isabelle, Crow Yanick J

Abstract excerpt

Fuelled by the on-going sequencing revolution, the last two years have seen a number of exciting discoveries relating to monogenic disorders predisposing to autoimmunity that provide new insights into the function of the human immune system. Here we discuss a selection of these diseases due to mutations in PRKCD, CTLA4, STAT3, IFIH1, TMEM173 and COPA.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26262888
DOI: 10.1016/j.coi.2015.07.008

Genes

COPA
CTLA4
IFIH1
PRKCD
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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