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Article

Further evidence for an association of ABCR alleles with age-related macular degeneration. The International ABCR Screening Consortium.

American journal of human genetics - 1 Aug 2000

Allikmets R

Abstract excerpt

Age-related macular degeneration (AMD) accounts for >50% of the registered visual disability among North American and Western European populations and has been associated both with environmental factors, such as smoking, and with genetic factors. Previously we have reported disease-associated variants in the ABCR (also called ABCA4) gene in a subset of patients affected with this complex disorder. We have now...

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Identifiers

PMID: 10880298
DOI: 10.1086/303018
PMCID: PMC1287193

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Further evidence for an association of ABCR alleles with age-related macular degeneration. The International ABCR Screening Consortium.PMID 10880298Read ↗

Associations of the G1961E and D2177N variants in ABCA4 and the risk of age-related macular degeneration.Semantic proximity Read ↗

Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration.Semantic proximity Read ↗

Mutation of the Stargardt Disease Gene (ABCR) in Age-related Macular DegenerationSemantic proximity Read ↗

Cosegregation and functional analysis of mutant ABCR (ABCA4) alleles in families that manifest both Stargardt disease and age-related macular degeneration.Semantic proximity Read ↗

Association of genetic variants at CETP, AGER, and CYP4F2 locus with the risk of atrophic age-related macular degeneration.Semantic proximity Read ↗

Correlation between the interactions of ABCA4 polymorphisms and smoking with the susceptibility to age-related macular degeneration.Semantic proximity Read ↗

Genetic susceptibility to age related macular degeneration.Semantic proximity Read ↗

Biochemical defects in ABCR protein variants associated with human retinopathies.Semantic proximity Read ↗

Allelic variation in ABCR associated with Stargardt disease but not age-related macular degenerationSemantic proximity Read ↗

Frequent hypomorphic alleles account for a significant fraction of ABCA4 disease and distinguish it from age-related macular degeneration.Semantic proximity Read ↗

ABCA1 rs1883025 polymorphism and risk of age-related macular degeneration.Semantic proximity Read ↗

The ABCR gene: a major disease gene in macular and peripheral retinal degenerations with onset from early childhood to the elderly.Semantic proximity Read ↗

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