Article
MicroRNA-200c overexpression inhibits chemoresistance, invasion and colony formation of human pancreatic cancer stem cells.
International journal of clinical and experimental pathology - 1 Jan 2015
Ma Chao, Huang Tao, Ding Yue-Chao, Yu Wei, Wang Qian, Meng Bo, Luo Su-Xia
Abstract excerpt
INTRODUCTION: Cancer stem cells (CSCs) are believed to be 'seed cell' in cancer recurrence and metastasis. MicroRNAs (miRNAs) have emerged as potential therapeutic candidates due to their ability to regulate multiple targets involved in tumor progression and chemoresistance. The goal of this study was to investigate the role of miRNA-200c (miR-200c) in regulating colony formation, invasion and chemoresistance of...
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