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Article

MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer.

Cancer letters - 28 Jan 2015

Jiang Jianxin, Li Zhu, Yu Chao, Chen Meiyuan, Tian Se, Sun Chengyi

Abstract excerpt

Recent studies have shown that cancer stem cells (CSCs) play an important role in the development of pancreatic cancer. Multiple oncogenes and signaling pathways have been confirmed to participate in the stemness maintenance and tumorigenicity of CSCs, including sex-determining region Y-box 2 (SOX2) and signal transduction and activation of transcription 3 (STAT3), which may provide novel therapeutic targets on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25444909
DOI: 10.1016/j.canlet.2014.11.007

Genes

SOX2
STAT3

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