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Article

Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer.

Stem cells and development - 15 Aug 2014

Bao Bin, Ali Shadan, Ahmad Aamir, Li Yiwei, Banerjee Sanjeev, Kong Dejuan, Aboukameel Amro, Mohammad Ramzi, Van Buren Eric, Azmi Asfar S, Sarkar Fazlul H

Abstract excerpt

Pancreatic cancer (PC) is one of the most deadly cancers. The higher mortality is in part due to treatment resistance and early onset of metastasis. The existence of cancer-stem-like cells (CSLCs) has been widely accepted to be responsible for tumor aggressiveness in PC. Emerging evidence suggests that CSLCs have the capacity for increased cell growth, cell migration/invasion, metastasis, and treatment...

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PMID: 24734907
DOI: 10.1089/scd.2013.0551

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