Article
PfeT, a P1B4 -type ATPase, effluxes ferrous iron and protects Bacillus subtilis against iron intoxication.
Molecular microbiology - 1 Nov 2015
Guan Guohua, Pinochet-Barros Azul, Gaballa Ahmed, Patel Sarju J, Argüello José M, Helmann John D
Abstract excerpt
Iron is an essential element for nearly all cells and limited iron availability often restricts growth. However, excess iron can also be deleterious, particularly when cells expressing high affinity iron uptake systems transition to iron rich environments. Bacillus subtilis expresses numerous iron importers, but iron efflux has not been reported. Here, we describe the B. subtilis PfeT protein (formerly YkvW/ZosA)...
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