Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

10 Aug 2015

Abstract excerpt

BACKGROUND: Previous studies have demonstrated that the trafficking defects of Nav1.1/Nav1.2 are involved in the dementia pathophysiology. However, the detailed mechanisms are not fully understood. Moreover, whether the impaired miRNAs regulation linked to dementia is a key player in sodium channel trafficking disturbance remains unclear. The cognitive impairment induced by chronic cerebral ischemia through...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Neurological Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26259688
DOI: 10.1186/s13024-015-0032-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusionPMID 26259688Read ↗

Hippocampal Transcriptome Profiling Reveals Common Disease Pathways in Chronic Hypoperfusion and AgeingSemantic proximity Read ↗

Alterations of Cerebral Extracellular Vesicle microRNA Profiling Potentially Disrupts Brain Homeostasis Following Myocardial InfarctionSemantic proximity Read ↗

The developmental changes of Nav1.1 and Nav1.2 expression in the human hippocampus and temporal lobeSemantic proximity Read ↗

miR-161 inhibits ferroptosis by targeting EGLN2 in vascular dementia rat modelSemantic proximity Read ↗

Mir155hg accelerates hippocampal neuron injury in convulsive status epilepticus by inhibiting microglial phagocytosisSemantic proximity Read ↗

Investigating the role of TREM2 and neuroinflammation in an experimental model of chronic cerebral hypoperfusionSemantic proximity Read ↗

Knockdown of lncRNA Gm11974 protect against cerebral ischemic reperfusion through miR-766-3p/NR3C2 axisSemantic proximity Read ↗

Caveolin-1 mediates neuroinflammation and cognitive impairment in SARS-CoV-2 infectionSemantic proximity Read ↗

SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathwaySemantic proximity Read ↗

Mfsd2a (Major Facilitator Superfamily Domain Containing 2a) Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Disruption by Inhibiting Vesicular Transcytosis.Semantic proximity Read ↗

Vasopressin Hypersecretion-Associated Brain Edema Formation in Ischemic Stroke: Underlying Mechanisms.Semantic proximity Read ↗

Moyamoya disease-specific extracellular vesicle-derived microRNAs in the cerebrospinal fluid as revealed by comprehensive expression analysis through microRNA sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.