miR-161 inhibits ferroptosis by targeting EGLN2 in vascular dementia rat model

Abstract excerpt

<title>Abstract</title> <p>Vascular dementia (VD) was characterized by both motor and non-motor dysfunctions and accounts for approximately 20% of dementia patients. Although VD has been given enormous attention owing to its high morbidity and severe consequence, the pathologic mechanisms of VD remain unclear. In this study, the bilateral common carotid artery occlusion (2-VO) rat, which has similar symptoms to V...

Topics

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• Cancer-related molecular mechanisms research
• Cerebrovascular Disorders
• Circular RNAs in diseases
• Ferroptosis and cancer prognosis
• Hemangioma, Cavernous, Central Nervous System
• Inflammation
• MicroRNA in disease regulation
• Mutation

Identifiers and source

Literature Corpus work

6558785c-b7b9-5cbe-b3a2-84033b6d46e0

DOI

10.21203/rs.3.rs-4742795/v1