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Article

HIV-1 Dual Infected LTNP-EC Patients Developed an Unexpected Antibody Cross-Neutralizing Activity.

PloS one - 1 Jan 2015

Pernas Maria, Sanchez-Merino Victor, Casado Concepcion, Merino-Mansilla Alberto, Olivares Isabel, Yuste Eloisa, Lopez-Galindez Cecilio

Abstract excerpt

This study evaluated the neutralization breadth in dually infected (DI) HIV-1 long-term non-progressor elite controller patients (LTNP-EC) using a representative minipanel of 6 viruses from 5 different subtypes. Our results showed an improved neutralization breadth in DI LTNP-EC patients when compared with matched LTNP single-infected patients. The role of viral diversity in neutralization was estimated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26258485
DOI: 10.1371/journal.pone.0134054
PMCID: PMC4530867

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