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Article

Tumor genotype determines phenotype and disease-related outcomes in thyroid cancer: a study of 1510 patients.

Annals of surgery - 1 Sept 2015

Yip Linwah, Nikiforova Marina N, Yoo Jenny Y, McCoy Kelly L, Stang Michael T, Armstrong Michaele J, Nicholson Kristina J, Ohori N Paul, Coyne Christopher, Hodak Steven P, Ferris Robert L, LeBeau Shane O, Nikiforov Yuri E, Carty Sally E

Abstract excerpt

OBJECTIVES: To correlate thyroid cancer genotype with histology and outcomes. BACKGROUND: The prognostic significance of molecular signature in thyroid cancer (TC) is undefined but can potentially change surgical management. METHODS: We reviewed a consecutive series of 1510 patients who had initial thyroidectomy for TC with routine testing for BRAF, RAS, RET/PTC, and PAX8/PPARG alterations. Histologic metastatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26258321
DOI: 10.1097/SLA.0000000000001420
PMCID: PMC5264519

Genes

RET
PAX8
PPARG
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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