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Association of BRAF V600E Allele Frequency With Clinicopathologic Outcomes in Papillary Thyroid Cancer

14 Nov 2024

Abstract excerpt

CONTEXT: BRAF V600E mutation is the most common genetic driver of papillary thyroid cancer (PTC), where it is found with various allele frequency (AF), reflecting the proportion of cells carrying the mutant and wild-type gene alleles. OBJECTIVE: To determine whether BRAF V600E AF can improve prognostication and inform initial surgical management of PTC. METHODS: This retrospective cohort study (2016-2019) at UCLA...

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PMID: 39541427
DOI: 10.1210/clinem/dgae774

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