Article
Genetics of oxidative stress in obesity.
International journal of molecular sciences - 20 Feb 2014
Rupérez Azahara I, Gil Angel, Aguilera Concepción M
Abstract excerpt
Obesity is a multifactorial disease characterized by the excessive accumulation of fat in adipose tissue and peripheral organs. Its derived metabolic complications are mediated by the associated oxidative stress, inflammation and hypoxia. Oxidative stress is due to the excessive production of reactive oxygen species or diminished antioxidant defenses. Genetic variants, such as single nucleotide polymorphisms in...
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