Article
Genetics and Genetic Testing in Pancreatic Cancer.
Gastroenterology - 1 Oct 2015
Whitcomb David C, Shelton Celeste A, Brand Randall E
Abstract excerpt
Genetic testing of germline DNA is used in patients suspected of being at risk of pancreatic ductal adenocarcinoma (PDAC) to better define the individual's risk and to determine the mechanism of risk. A high genetic risk increases the pretest probability that a biomarker of early cancer is a true positive and warrants further investigation. The highest PDAC risk is generally associated with a hereditary...
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