Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung.

PloS one - 1 Jan 2015

Harmer Christopher J, Wynn Matthew, Pinto Rachel, Cordwell Stuart, Rose Barbara R, Harbour Colin, Triccas James A, Manos Jim

Abstract excerpt

Some Pseudomonas aeruginosa strains including Australian Epidemic Strain-1 (AES-1 or AUS-01) cause persistent chronic infection in cystic fibrosis (CF) patients, with greater morbidity and mortality. Factors conferring persistence are largely unknown. Previously we analysed the transcriptomes of AES-1 grown in Luria broth, nematode growth medium for Caenorhabditis elegans assay (both aerobic) and artificial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Australia
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis

Share to Epidemics

Share to Immunophenotyping

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 26252386
DOI: 10.1371/journal.pone.0134229
PMCID: PMC4529145

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Homogentisate 1-2-Dioxygenase Downregulation in the Chronic Persistence of Pseudomonas aeruginosa Australian Epidemic Strain-1 in the CF Lung.PMID 26252386Read ↗

Pseudomonas aeruginosa AES-1 Exhibits Increased Virulence Gene Expression during Chronic Infection of Cystic Fibrosis LungSemantic proximity Read ↗

Modulation of gene expression by Pseudomonas aeruginosa during chronic infection in the adult cystic fibrosis lungSemantic proximity Read ↗

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts.Semantic proximity Read ↗

Long-term adaptation to hypoxia provides insight into mechanisms facilitating the switch of <i>Pseudomonas aeruginosa</i> to chronic lung infectionsSemantic proximity Read ↗

Atypical BlaIR Two-Component System in <i>Pseudomonas aeruginosa</i> Regulates Virulence but not β-Lactam ResistanceSemantic proximity Read ↗

Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lungSemantic proximity Read ↗

<i>Pseudomonas aeruginosa</i> isolates co-incubated with <i>Acanthamoeba castellanii</i> exhibit phenotypes similar to chronic cystic fibrosis isolatesSemantic proximity Read ↗

Proteomics of <i>Pseudomonas aeruginosa</i> Australian Epidemic Strain 1 (AES-1) Cultured under Conditions Mimicking the Cystic Fibrosis Lung Reveals Increased Iron Acquisition via the Siderophore PyochelinSemantic proximity Read ↗

A Subtype of aPseudomonas aeruginosaCystic Fibrosis Epidemic Strain Exhibits Enhanced Virulence in a Murine Model of Acute Respiratory InfectionSemantic proximity Read ↗

Proteomic profiling of Pseudomonas aeruginosa AES-1R, PAO1 and PA14 reveals potential virulence determinants associated with a transmissible cystic fibrosis-associated strainSemantic proximity Read ↗

Inflammation-like environments limit the loss of quorum sensing in Pseudomonas aeruginosa.Semantic proximity Read ↗

Response of Pseudomonas aeruginosa to the Innate Immune System-Derived Oxidants Hypochlorous Acid and Hypothiocyanous Acid.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.