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Article

Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome

7 Aug 2015

Abstract excerpt

Inter-α-trypsin inhibitor heavy chain 5 (ITIH5) is supposed to be involved in extracellular matrix stability and thus may play a key role in the inhibition of tumor progression. The current study is the first to analyze in depth ITIH5 expression and DNA methylation, as well as its potential clinical impact in non-small-cell lung carcinoma (NSCLC). We examined ITIH5 mRNA expression in tumor and adjacent normal...

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Identifiers

PMID: 26252352
DOI: 10.1080/15592294.2015.1078049

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