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High-Content Assay for Measuring Intracellular Growth of Leishmania in Human Macrophages

6 Aug 2015

Abstract excerpt

Leishmania species are sandfly-transmitted protozoan parasites that cause a spectrum of diseases, ranging from localized skin lesions to fatal visceral disease, in more than 12 million people worldwide. These parasites primarily target macrophages in their mammalian hosts and proliferate as non-motile amastigotes in the phagolysosomal compartment of these cells. High-throughput screens for measuring Leishmania...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26247370
DOI: 10.1089/adt.2015.652

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