Article
Geography of follicle formation in the embryonic mouse ovary impacts activation pattern during the first wave of folliculogenesis.
Biology of reproduction - 1 Oct 2015
Cordeiro Marília H, Kim So-Youn, Ebbert Katherine, Duncan Francesca E, Ramalho-Santos João, Woodruff Teresa K
Abstract excerpt
During embryonic development, mouse female germ cells enter meiosis in an anterior-to-posterior wave believed to be driven by retinoic acid. It has been proposed that ovarian follicle formation and activation follow the same general wave of meiotic progression; however, the precise anatomic specification of these processes has not been delineated. Here, we created a mouse line using Mvh, Gdf9, and Zp3 promoters...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
