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Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection

6 Aug 2015

Abstract excerpt

Influenza A H1N1/2009 virus that emerged from swine rapidly replaced the previous seasonal H1N1 virus. Although the early emergence and diversification of H1N1/2009 is well characterized, the ongoing evolutionary and global transmission dynamics of the virus remain poorly investigated. To address this we analyse >3,000 H1N1/2009 genomes, including 214 full genomes generated from our surveillance in Singapore, in...

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PMID: 26245473
DOI: 10.1038/ncomms8952

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